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PD-1 regulates extrathymic regulatory T-cell differentiation
Regulatory T (Treg) cells and the programmed death-1/programmed death ligand-1 (PD-1/PD-L1) pathway are both critical for maintaining peripheral tolerance to self antigens. A significant subset of Treg cells constitutively expresses PD-1, which prompted an investigation into the role of PD-1/PD-L1 i...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4165701/ https://ncbi.nlm.nih.gov/pubmed/24975127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201344423 |
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