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Nrf2, a regulator of the proteasome, controls self-renewal and pluripotency in human embryonic stem cells
Nuclear factor, erythroid 2-like 2 (Nrf2) is a master transcription factor for cellular defense against endogenous and exogenous stresses by regulating expression of many antioxidant and detoxification genes. Here, we show that Nrf2 acts as a key pluripotency gene and a regulator of proteasome activ...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4165656/ https://ncbi.nlm.nih.gov/pubmed/24895273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1764 |
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