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Selective Mitogen Activated Protein Kinase Activity Sensors through the Application of Directionally Programmable D Domain Motifs

[Image: see text] Accurate and quantitative methods for measuring the dynamic fluctuations of protein kinase activities are critically needed as diagnostic tools and for the evaluation of kinase-targeted inhibitors, which represent a major therapeutic development area in the treatment of cancer and...

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Autors principals: Peterson, Laura B., Yaffe, Michael B., Imperiali, Barbara
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4165445/
https://ncbi.nlm.nih.gov/pubmed/25153342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500862c
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