A Residue Quartet in the Extracellular Domain of the Prolactin Receptor Selectively Controls Mitogen-activated Protein Kinase Signaling

Cytokine receptors elicit several signaling pathways, but it is poorly understood how they select and discriminate between them. We have scrutinized the prolactin receptor as an archetype model of homodimeric cytokine receptors to address the role of the extracellular membrane proximal domain in sig...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zhang, Chi, Nygaard, Mads, Haxholm, Gitte W., Boutillon, Florence, Bernadet, Marie, Hoos, Sylviane, England, Patrick, Broutin, Isabelle, Kragelund, Birthe B., Goffin, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424329/
https://ncbi.nlm.nih.gov/pubmed/25784554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.639096
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