A Residue Quartet in the Extracellular Domain of the Prolactin Receptor Selectively Controls Mitogen-activated Protein Kinase Signaling

Cytokine receptors elicit several signaling pathways, but it is poorly understood how they select and discriminate between them. We have scrutinized the prolactin receptor as an archetype model of homodimeric cytokine receptors to address the role of the extracellular membrane proximal domain in sig...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Zhang, Chi, Nygaard, Mads, Haxholm, Gitte W., Boutillon, Florence, Bernadet, Marie, Hoos, Sylviane, England, Patrick, Broutin, Isabelle, Kragelund, Birthe B., Goffin, Vincent
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2015
Konular:
Signal Transduction
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424329/
https://ncbi.nlm.nih.gov/pubmed/25784554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.639096
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