A Residue Quartet in the Extracellular Domain of the Prolactin Receptor Selectively Controls Mitogen-activated Protein Kinase Signaling

Cytokine receptors elicit several signaling pathways, but it is poorly understood how they select and discriminate between them. We have scrutinized the prolactin receptor as an archetype model of homodimeric cytokine receptors to address the role of the extracellular membrane proximal domain in sig...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Zhang, Chi, Nygaard, Mads, Haxholm, Gitte W., Boutillon, Florence, Bernadet, Marie, Hoos, Sylviane, England, Patrick, Broutin, Isabelle, Kragelund, Birthe B., Goffin, Vincent
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2015
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424329/
https://ncbi.nlm.nih.gov/pubmed/25784554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.639096
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