PB1-F2, an Influenza A Virus-Encoded Proapoptotic Mitochondrial Protein, Creates Variably Sized Pores in Planar Lipid Membranes

A frameshifted region of the influenza A virus PB1 gene encodes a novel protein, termed PB1-F2, a mitochondrial protein that can induce cell death. Many proapoptotic proteins are believed to act at the mitochondrial outer membrane to form an apoptotic pore with lipids. We studied the interaction of...

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Bibliographic Details
Main Authors: Chanturiya, A. N., Basañez, G., Schubert, U., Henklein, P., Yewdell, J. W., Zimmerberg, J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC416516/
https://ncbi.nlm.nih.gov/pubmed/15163724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.12.6304-6312.2004
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