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Metabolism and Disposition of Bupropion in Pregnant Baboons (Papio cynocephalus)

Recent in vitro data obtained in our laboratory revealed similarities between baboons and humans in the biotransformation of bupropion (BUP) by both hepatic and placental microsomes. These data supported the use of baboons to study BUP biotransformation during pregnancy. The aim of this investigatio...

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Bibliographische Detailangaben
Hauptverfasser: Rytting, Erik, Wang, Xiaoming, Vernikovskaya, Daria I., Zhan, Ying, Bauer, Cassondra, Abdel-Rahman, Susan M., Ahmed, Mahmoud S., Nanovskaya, Tatiana N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164976/
https://ncbi.nlm.nih.gov/pubmed/25097227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.114.058255
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