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Metabolism and Disposition of Bupropion in Pregnant Baboons (Papio cynocephalus)

Recent in vitro data obtained in our laboratory revealed similarities between baboons and humans in the biotransformation of bupropion (BUP) by both hepatic and placental microsomes. These data supported the use of baboons to study BUP biotransformation during pregnancy. The aim of this investigatio...

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Autors principals: Rytting, Erik, Wang, Xiaoming, Vernikovskaya, Daria I., Zhan, Ying, Bauer, Cassondra, Abdel-Rahman, Susan M., Ahmed, Mahmoud S., Nanovskaya, Tatiana N.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164976/
https://ncbi.nlm.nih.gov/pubmed/25097227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.114.058255
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