The translation elongation factor eEF1A1 couples transcription to translation during heat shock response

Translation elongation factor eEF1A has a well-defined role in protein synthesis. In this study, we demonstrate a new role for eEF1A: it participates in the entire process of the heat shock response (HSR) in mammalian cells from transcription through translation. Upon stress, isoform 1 of eEF1A rapi...

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Hlavní autoři: Vera, Maria, Pani, Bibhusita, Griffiths, Lowri A, Muchardt, Christian, Abbott, Catherine M, Singer, Robert H, Nudler, Evgeny
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2014
Témata:
Biochemistry
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164936/
https://ncbi.nlm.nih.gov/pubmed/25233275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03164
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