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Mechanistic Insights into Transcription Coupled DNA Repair

Transcription-coupled DNA repair (TCR) acts on lesions in the transcribed strand of active genes. Helix distorting adducts and other forms of DNA damage often interfere with the progression of the transcription apparatus. Prolonged stalling of RNA polymerase can promote genome instability and also i...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Pani, Bibhusita, Nudler, Evgeny
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538147/
https://ncbi.nlm.nih.gov/pubmed/28629777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.06.006
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