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Mechanistic Insights into Transcription Coupled DNA Repair

Transcription-coupled DNA repair (TCR) acts on lesions in the transcribed strand of active genes. Helix distorting adducts and other forms of DNA damage often interfere with the progression of the transcription apparatus. Prolonged stalling of RNA polymerase can promote genome instability and also i...

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Détails bibliographiques
Publié dans:DNA Repair (Amst)
Auteurs principaux: Pani, Bibhusita, Nudler, Evgeny
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538147/
https://ncbi.nlm.nih.gov/pubmed/28629777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.06.006
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