Neurokinin B Induces c-fos Transcription via Protein Kinase C and Activation of Serum Response Factor and Elk-1 in Immortalized GnRH Neurons

Mutations in neurokinin B (NKB) and its receptor, NK3R, were identified in human patients with hypogonadotropic hypogonadism, a disorder characterized by lack of puberty and infertility. Further studies have suggested that NKB acts at the level of the hypothalamus to control GnRH neuron activity, ei...

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Autores principales: Glidewell-Kenney, Christine A., Trang, Crystal, Shao, Paul P., Gutierrez-Reed, Navarre, Uzo-Okereke, Adaku M., Coss, Djurdjica, Mellon, Pamela L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2014
Materias:
Neuroendocrinology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164922/
https://ncbi.nlm.nih.gov/pubmed/25057795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1263
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