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Cdk5-mediated phosphorylation of RapGEF2 controls neuronal migration in the developing cerebral cortex

During cerebral cortex development, pyramidal neurons migrate through the intermediate zone and integrate into the cortical plate. These neurons undergo the multipolar–bipolar transition to initiate radial migration. While perturbation of this polarity acquisition leads to cortical malformations, ho...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ye, Tao, Ip, Jacque P. K., Fu, Amy K. Y., Ip, Nancy Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Pub. Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164783/
https://ncbi.nlm.nih.gov/pubmed/25189171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5826
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