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Identification of TERRA locus unveils a telomere protection role through association to nearly all chromosomes

Telomeric RNAs (TERRAs) are UUAGGG repeat-containing RNAs that are transcribed from the subtelomere towards the telomere. The precise genomic origin of TERRA has remained elusive. Using a whole-genome RNA-sequencing approach, we identify novel mouse transcripts arising mainly from the subtelomere of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: de Silanes, Isabel López, Graña, Osvaldo, De Bonis, Maria Luigia, Dominguez, Orlando, Pisano, David G, Blasco, Maria A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Pub. Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164772/
https://ncbi.nlm.nih.gov/pubmed/25182072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5723
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