Structural Basis for Substrate Specificity of Mammalian Neuraminidases

The removal of sialic acid (Sia) residues from glycoconjugates in vertebrates is mediated by a family of neuraminidases (sialidases) consisting of Neu1, Neu2, Neu3 and Neu4 enzymes. The enzymes play distinct physiological roles, but their ability to discriminate between the types of linkages connect...

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Detalhes bibliográficos
Principais autores: Smutova, Victoria, Albohy, Amgad, Pan, Xuefang, Korchagina, Elena, Miyagi, Taeko, Bovin, Nicolai, Cairo, Christopher W., Pshezhetsky, Alexey V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164519/
https://ncbi.nlm.nih.gov/pubmed/25222608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106320
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