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Neuraminidase 1 activates insulin receptor and reverses insulin resistance in obese mice
Objectives: Neuraminidase 1 (NEU1) cleaves terminal sialic acids of glycoconjugates during lysosomal catabolism. It also modulates the structure and activity of cellular surface receptors affecting diverse pathways. Previously we demonstrated that NEU1 activates the insulin receptor (IR) and that NE...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2018-06-01
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Colecção: | Molecular Metabolism |
Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S2212877817310748 |
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