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Functional DNA methylation in a transcript specific 3′UTR region of TrkB associates with suicide
Previous studies indicate that a subgroup of suicide completers has low cortical brain expression levels of TrkB-T1, a TrkB gene transcript that is highly expressed in astrocytes. Epigenetic modifications, including methylation changes in the TrkB promoter, partially explain TrkB-T1 low expression l...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4164491/ https://ncbi.nlm.nih.gov/pubmed/24802768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.29068 |
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