A systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics

In complex biological systems, small molecules often mediate microbe-microbe and microbe-host interactions. Using a systematic approach, we identified 3,118 small molecule biosynthetic gene clusters (BGCs) in genomes of human-associated bacteria and studied their representation in 752 metagenomic sa...

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Bibliografiset tiedot
Päätekijät: Donia, Mohamed S., Cimermancic, Peter, Schulze, Christopher J., Wieland Brown, Laura C., Martin, John, Mitreva, Makedonka, Clardy, Jon, Linington, Roger G., Fischbach, Michael A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164201/
https://ncbi.nlm.nih.gov/pubmed/25215495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.08.032
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