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A comprehensive evaluation of collapsing methods using simulated and real data: excellent annotation of functionality and large sample sizes required
The advent of next generation sequencing (NGS) technologies enabled the investigation of the rare variant-common disease hypothesis in unrelated individuals, even on the genome-wide level. Analysis of this hypothesis requires tailored statistical methods as single marker tests fail on rare variants....
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Frontiers Media S.A.
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4164031/ https://ncbi.nlm.nih.gov/pubmed/25309579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00323 |
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