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Comparison of collapsing methods for the statistical analysis of rare variants

Novel technologies allow sequencing of whole genomes and are considered as an emerging approach for the identification of rare disease-associated variants. Recent studies have shown that multiple rare variants can explain a particular proportion of the genetic basis for disease. Following this assum...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Dering, Carmen, Ziegler, Andreas, König, Inke R, Hemmelmann, Claudia
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287839/
https://ncbi.nlm.nih.gov/pubmed/22373249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S115
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