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Statistical Analysis of Rare Sequence Variants: An Overview of Collapsing Methods
With the advent of novel sequencing technologies, interest in the identification of rare variants that influence common traits has increased rapidly. Standard statistical methods, such as the Cochrane-Armitage trend test or logistic regression, fail in this setting for the analysis of unrelated subj...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3277891/ https://ncbi.nlm.nih.gov/pubmed/22128052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20643 |
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