Demethylation of CpG islands in the 5' upstream regions mediates the expression of the human testis-specific gene MAGEB16 and its mouse homolog Mageb16

Tissue-specific gene expression is regulated by epigenetic modification involving trans-acting factors. Here, we identified that the human MAGEB16 gene and its mouse homolog, Mageb16, are only expressed in the testis. To investigate the mechanism governing their expression, the promoter methylation...

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Detalhes bibliográficos
Main Authors: Liu, Yunqiang, Wang, Meiling, Jiang, Siyuan, Lu, Yongjie, Tao, Dachang, Yang, Yuan, Ma, Yongxin, Zhang, Sizhong
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Biochemistry and Molecular Biology 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163901/
https://ncbi.nlm.nih.gov/pubmed/24219866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2014.47.2.066
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