A paradigm for drug discovery employing encoded combinatorial libraries.

Very large combinatorial libraries of small molecules on solid supports can now be synthesized and each library element can be identified after synthesis by using chemical tags. These tag-encoded libraries are potentially useful in drug discovery, and, to test this utility directly, we have targeted...

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Bibliografiske detaljer
Main Authors: Burbaum, J J, Ohlmeyer, M H, Reader, J C, Henderson, I, Dillard, L W, Li, G, Randle, T L, Sigal, N H, Chelsky, D, Baldwin, J J
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC41635/
https://ncbi.nlm.nih.gov/pubmed/7597074
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