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An integrated analysis of the SOX2 microRNA response program in human pluripotent and nullipotent stem cell lines
BACKGROUND: SOX2 is a core component of the transcriptional network responsible for maintaining embryonal carcinoma cells (ECCs) in a pluripotent, undifferentiated state of self-renewal. As such, SOX2 is an oncogenic transcription factor and crucial cancer stem cell (CSC) biomarker in embryonal carc...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4162954/ https://ncbi.nlm.nih.gov/pubmed/25156079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-711 |
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