Loading...

Targeting the C-terminal focal adhesion kinase scaffold in pancreatic cancer

Preliminary studies in our laboratory have demonstrated the importance of both the NH2 and COOH terminus scaffolding functions of focal adhesion kinase (FAK). Here, we describe a new small molecule inhibitor, C10 that targets the FAK C-terminus scaffold. C10 showed marked selectivity for cells overe...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Gogate, Priyanka N., Kurenova, Elena V., Ethirajan, Manivannan, Liao, Jianqun, Yemma, Michael, Sen, Arindam, Pandey, Ravindra K., Cance, William G.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162749/
https://ncbi.nlm.nih.gov/pubmed/25067788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2014.07.032
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!