Application of apolipoprotein E-modified liposomal nanoparticles as a carrier for delivering DNA and nucleic acid in the brain

An innovative drug delivery technology is urgently needed to satisfy unmet medical needs in treating various brain disorders. As a fundamental carrier for plasmid DNA or nucleic acids, we developed a liposomal nanoparticle (multifunctional envelope-type nano device [MEND]) containing a proton-ioniza...

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Main Authors: Tamaru, Mina, Akita, Hidetaka, Nakatani, Taichi, Kajimoto, Kazuaki, Sato, Yusuke, Hatakeyama, Hiroto, Harashima, Hideyoshi
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2014
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162633/
https://ncbi.nlm.nih.gov/pubmed/25228805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S65402
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