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Modifying Antigen-Encapsulating Liposomes with KALA Facilitates MHC Class I Antigen Presentation and Enhances Anti-tumor Effects

For a successful anti-cancer vaccine, antigen presentation on the major histocompatibility complex (MHC) class I is a requirement. To accomplish this, an antigen must be delivered to the cytoplasm by overcoming the endosome/lysosome. We previously reported that a lipid nanoparticle modified with a K...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Miura, Naoya, Akita, Hidetaka, Tateshita, Naho, Nakamura, Takashi, Harashima, Hideyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383577/
https://ncbi.nlm.nih.gov/pubmed/28236573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.01.020
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