Src-mediated Post-translational Regulation of Endoglin Stability and Function Is Critical for Angiogenesis

Endoglin is a transforming growth factor β (TGF-β) co-receptor essential for angiogenesis and tumor vascularization. Endoglin modulates the crucial balance between pro- and anti-angiogenic signaling by activin receptor-like kinase (ALK) 1, 5, and TGF-β type II (TβRII) receptors. Despite its establis...

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Hlavní autoři: Pan, Christopher C., Kumar, Sanjay, Shah, Nirav, Hoyt, Dale G., Hawinkels, Lukas J. A. C., Mythreye, Karthikeyan, Lee, Nam Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162155/
https://ncbi.nlm.nih.gov/pubmed/25070888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.578609
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