Activation of mitofusin2 by Smad2-RIN1 complex during mitochondrial fusion

Smads are nuclear-shuttling transcriptional mediators of transforming growth factor-β (TGF-β) signaling. While their essential nuclear roles in gene regulation during development and carcinogenesis are well established, whether they have important cytoplasmic functions remains unclear. Here we repor...

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Udgivet i:Mol Cell
Main Authors: Kumar, Sanjay, Pan, Christopher C., Shah, Nirav, Wheeler, Sarah E., Hoyt, Kari R., Hempel, Nadine, Mythreye, Karthikeyan, Lee, Nam Y.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4877164/
https://ncbi.nlm.nih.gov/pubmed/27184078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.04.010
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