Inhibition of Epithelial to Mesenchymal Transition by E-cadherin Up-regulation via Repression of Slug Transcription and Inhibition of E-cadherin Degradation: DUAL ROLE OF SCAFFOLD/MATRIX ATTACHMENT REGION-BINDING PROTEIN 1 (SMAR1) IN BREAST CANCER CELLS

The evolution of the cancer cell into a metastatic entity is the major cause of death in patients with cancer. It has been acknowledged that aberrant activation of a latent embryonic program, known as the epithelial-mesenchymal transition (EMT), can endow cancer cells with the migratory and invasive...

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Main Authors: Adhikary, Arghya, Chakraborty, Samik, Mazumdar, Minakshi, Ghosh, Swatilekha, Mukherjee, Shravanti, Manna, Argha, Mohanty, Suchismita, Nakka, Kiran Kumar, Joshi, Shruti, De, Abhijit, Chattopadhyay, Samit, Sa, Gaurisankar, Das, Tanya
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Molecular Bases of Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162148/
https://ncbi.nlm.nih.gov/pubmed/25086032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.527267
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