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Nuclear Matrix Protein SMAR1 Represses c-Fos-mediated HPV18 E6 Transcription through Alteration of Chromatin Histone Deacetylation

Matrix attachment region (MAR)-binding proteins have been implicated in the transcriptional regulation of host as well as viral genes, but their precise role in HPV-infected cervical cancer remains unclear. Here we show that HPV18 promoter contains consensus MAR element in the LCR and E6 sequences w...

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Detalhes bibliográficos
Main Authors: Chakraborty, Samik, Das, Kaushik, Saha, Shilpi, Mazumdar, Minakshi, Manna, Argha, Chakraborty, Sreeparna, Mukherjee, Shravanti, Khan, Poulami, Adhikary, Arghya, Mohanty, Suchismita, Chattopadhyay, Samit, Biswas, Subhash C., Sa, Gaurisankar, Das, Tanya
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200262/
https://ncbi.nlm.nih.gov/pubmed/25157104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.564872
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