Aspirin inhibits epithelial-to-mesenchymal transition and migration of oncogenic K-ras-expressing non-small cell lung carcinoma cells by down-regulating E-cadherin repressor Slug

BACKGROUND: Cancer metastasis is one of the most common causes of treatment failure and death in cancer patients. It has been acknowledged that aberrant activation of epithelial-to-mesenchymal transition (EMT) program, endows cancer cells with metastatic competence for which E-cadherin switch is a w...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Khan, Poulami, Manna, Argha, Saha, Shilpi, Mohanty, Suchismita, Mukherjee, Shravanti, Mazumdar, Minakshi, Guha, Deblina, Das, Tanya
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727308/
https://ncbi.nlm.nih.gov/pubmed/26810856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2078-7
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