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Randomized, placebo-controlled trial to assess the safety and immunogenicity of an adenovirus type 35-based circumsporozoite malaria vaccine in healthy adults

Malaria results in over 650 000 deaths each year; thus, there is an urgent need for an effective vaccine. Pre-clinical studies and recently reported human trials suggest that pre-erythrocytic stage vaccines can provide protection against infection. A Phase 1, randomized, placebo-controlled, dose-esc...

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Detalhes bibliográficos
Main Authors: Creech, C Buddy, Dekker, Cornelia L, Ho, Dora, Phillips, Shanda, Mackey, Sally, Murray-Krezan, Cristina, Grazia Pau, Maria, Hendriks, Jenny, Brown, Valerie, Dally, Leonard G, Versteege, Isabella, Edwards, Kathryn M
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162066/
https://ncbi.nlm.nih.gov/pubmed/23955431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.26038
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