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Notoginsenoside R1 increases neuronal excitability and ameliorates synaptic and memory dysfunction following amyloid elevation

Neurodegeneration and synaptic dysfunction observed in Alzheimer's disease (AD) have been associated with progressive decrease in neuronal activity. Here, we investigated the effects of Notoginsenoside R1 (NTR1), a major saponin isolated from Panax notoginseng, on neuronal excitability and asse...

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Detalhes bibliográficos
Main Authors: Yan, Shijun, Li, Zhi, Li, Hang, Arancio, Ottavio, Zhang, Wensheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161968/
https://ncbi.nlm.nih.gov/pubmed/25213453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06352
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