HE3286 Reduces Axonal Loss and Preserves Retinal Ganglion Cell Function in Experimental Optic Neuritis

PURPOSE. Optic nerve inflammation, demyelination, and axonal loss are all prominent features of optic neuritis. While corticosteroids hasten visual recovery in optic neuritis, no treatment improves final visual outcomes. HE3286 (17α-ethynyl-5-androstene-3β,7β,17β-triol), a synthetic derivative of a...

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Hauptverfasser: Khan, Reas S., Dine, Kimberly, Luna, Esteban, Ahlem, Clarence, Shindler, Kenneth S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Association for Research in Vision and Ophthalmology 2014
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161484/
https://ncbi.nlm.nih.gov/pubmed/25139738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-14672
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