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HE3286 Reduces Axonal Loss and Preserves Retinal Ganglion Cell Function in Experimental Optic Neuritis

PURPOSE. Optic nerve inflammation, demyelination, and axonal loss are all prominent features of optic neuritis. While corticosteroids hasten visual recovery in optic neuritis, no treatment improves final visual outcomes. HE3286 (17α-ethynyl-5-androstene-3β,7β,17β-triol), a synthetic derivative of a...

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Detalhes bibliográficos
Main Authors: Khan, Reas S., Dine, Kimberly, Luna, Esteban, Ahlem, Clarence, Shindler, Kenneth S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161484/
https://ncbi.nlm.nih.gov/pubmed/25139738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-14672
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