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Low Levels of p53 Protein and Chromatin Silencing of p53 Target Genes Repress Apoptosis in Drosophila Endocycling Cells

Apoptotic cell death is an important response to genotoxic stress that prevents oncogenesis. It is known that tissues can differ in their apoptotic response, but molecular mechanisms are little understood. Here, we show that Drosophila polyploid endocycling cells (G/S cycle) repress the apoptotic re...

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Bibliografische gegevens
Hoofdauteurs: Zhang, Bingqing, Mehrotra, Sonam, Ng, Wei Lun, Calvi, Brian R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161308/
https://ncbi.nlm.nih.gov/pubmed/25211335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004581
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