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Endocycling cells do not apoptose in response to DNA rereplication genotoxic stress
Initiation of DNA replication at origins more than once per cell cycle results in rereplication and has been implicated in cancer. Here we use Drosophila to examine the checkpoint responses to rereplication in a developmental context. We find that increased Double-parked (Dup), the Drosophila orthol...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2593612/ https://ncbi.nlm.nih.gov/pubmed/19056894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1710208 |
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