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Inflation and Long-Term Maintenance of CD8 T-Cells Responding to a Latent Herpesvirus Depend upon Establishment of Latency and Presence of Viral Antigens

Following the priming and contraction phases of the T-cell response, latent persistent herpesviruses lead to an accumulation of large pools of virus-specific CD8 T-cells, also known as memory inflation (MI). The mechanism of this inflation is incompletely understood, largely because molecular reacti...

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Bibliografiske detaljer
Main Authors: Lang, Anna, Brien, James D., Nikolich-Zugich, Janko
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161222/
https://ncbi.nlm.nih.gov/pubmed/20007576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0801117
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