Characterizing Solution Surface Loop Conformational Flexibility of the GM2 Activator Protein

[Image: see text] GM2AP has a β-cup topology with numerous X-ray structures showing multiple conformations for some of the surface loops, revealing conformational flexibility that may be related to function, where function is defined as either membrane binding associated with ligand binding and extr...

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Bibliografiske detaljer
Main Authors: Carter, Jeffery D., Mathias, Jordan D., Gomez, Edwin F., Ran, Yong, Xu, Fang, Galiano, Luis, Tran, Nguyen Q., D’Amore, Peter W., Wright, Christine S., Chakravorty, Dhruva K., Fanucci, Gail E.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161144/
https://ncbi.nlm.nih.gov/pubmed/25127419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp505938t
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