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Ligand Extraction Properties of the GM2 Activator Protein and Its Interactions with Lipid Vesicles

The GM2 activator protein (GM2AP) is an accessory protein required for the enzymatic conversion of GM2 to GM3 by hydrolases in the lysosomal compartments of cells. Here, GM2AP interactions with lipid vesicles are investigated by sucrose-loaded vesicle sedimentation and gel filtration assays, and the...

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Detalhes bibliográficos
Main Authors: Ran, Yong, Fanucci, Gail E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711380/
https://ncbi.nlm.nih.gov/pubmed/19580763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.03.065
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