Generation and Characterization of Ins1-cre-driver C57BL/6N for Exclusive Pancreatic Beta Cell-specific Cre-loxP Recombination

Cre/loxP system-mediated site-specific recombination is utilized to study gene function in vivo. Successful conditional knockout of genes of interest is dependent on the availability of Cre-driver mice. We produced and characterized pancreatic β cell-specific Cre-driver mice for use in diabetes mell...

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Hlavní autoři: Hasegawa, Yoshikazu, Daitoku, Yoko, Mizuno, Seiya, Tanimoto, Yoko, Mizuno-Iijima, Saori, Matsuo, Miki, Kajiwara, Noriko, Ema, Masatsugu, Oishi, Hisashi, Miwa, Yoshihiro, Mekada, Kazuyuki, Yoshiki, Atsushi, Takahashi, Satoru, Sugiyama, Fumihiro, Yagami, Ken-ichi
Médium: Artigo
Jazyk:Inglês
Vydáno: Japanese Association for Laboratory Animal Science 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160984/
https://ncbi.nlm.nih.gov/pubmed/24770644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1538/expanim.63.183
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