Peri-implantation lethality in mice carrying megabase-scale deletion on 5qc3.3 is caused by Exoc1 null mutation

We found a novel spontaneous mouse mutant with depigmentation in the ventral body, which we called White Spotting (WS) mouse. Genetic investigation revealed deletion of a > 1.2-Mb genomic region containing nine genes (Kit, Kdr, Srd5a3, Tmeme165, Clock, Pdcl2, Nmu, Exoc1, and Cep135). We designate...

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Publicado no:Sci Rep
Main Authors: Mizuno, Seiya, Takami, Kohei, Daitoku, Yoko, Tanimoto, Yoko, Dinh, Tra Thi Huong, Mizuno-Iijima, Saori, Hasegawa, Yoshikazu, Takahashi, Satoru, Sugiyama, Fumihiro, Yagami, Ken-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562154/
https://ncbi.nlm.nih.gov/pubmed/26346620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13632
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