Angiotensin-converting enzyme inhibition, but not AT(1) receptor blockade, in the solitary tract nucleus improves baroreflex sensitivity in anesthetized transgenic hypertensive (mRen2)27 rats

Transgenic hypertensive (mRen2)27 rats overexpress the murine Ren2 gene and have impaired baroreflex sensitivity (BRS) for control of the heart rate. Removal of endogenous angiotensin (Ang)-(1–7) tone using a receptor blocker does not further lower BRS. Therefore, we assessed whether blockade of Ang...

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Detalhes bibliográficos
Main Authors: Isa, Katsunori, Arnold, Amy C, Westwood, Brian M, Chappell, Mark C, Diz, Debra I
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160904/
https://ncbi.nlm.nih.gov/pubmed/21937997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hr.2011.110
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