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Angiotensin-(1–12) requires angiotensin converting enzyme and AT(1) receptors for cardiovascular actions within the solitary tract nucleus

The novel peptide, angiotensin (ANG)-(1–12), elicits a systemic pressor response and vasoconstriction. These effects are blocked by ANG converting enzyme (ACE) inhibitors or AT(1) receptor antagonists, suggesting a role as an ANG II precursor. However, ANG-(1–12) can serve as a substrate for either...

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Detalhes bibliográficos
Main Authors: Arnold, Amy C., Isa, Katsunori, Shaltout, Hossam A., Nautiyal, Manisha, Ferrario, Carlos M., Chappell, Mark C., Diz, Debra I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944473/
https://ncbi.nlm.nih.gov/pubmed/20562338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00345.2010
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