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PROTEIN PHOSPHATASE 1B IN THE SOLITARY TRACT NUCLEUS IS NECESSARY FOR NORMAL BAROREFLEX FUNCTION

Despite positive metabolic effects, genetic deletion of protein phosphatase 1b (PTP1b) results in sympathetically-mediated elevations in arterial pressure (AP) in mice. Since several PTP1b-regulated peptides also impair the baroreflex sensitivity (BRS) for control of heart rate (HR), we hypothesized...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Arnold, Amy C, Nautiyal, Manisha, Diz, Debra I
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349073/
https://ncbi.nlm.nih.gov/pubmed/22569287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0b013e31824ba490
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