Angiotensin-converting enzyme inhibition, but not AT(1) receptor blockade, in the solitary tract nucleus improves baroreflex sensitivity in anesthetized transgenic hypertensive (mRen2)27 rats

Transgenic hypertensive (mRen2)27 rats overexpress the murine Ren2 gene and have impaired baroreflex sensitivity (BRS) for control of the heart rate. Removal of endogenous angiotensin (Ang)-(1–7) tone using a receptor blocker does not further lower BRS. Therefore, we assessed whether blockade of Ang...

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Autors principals: Isa, Katsunori, Arnold, Amy C, Westwood, Brian M, Chappell, Mark C, Diz, Debra I
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160904/
https://ncbi.nlm.nih.gov/pubmed/21937997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hr.2011.110
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