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microRNA-17–92 Regulates IL-10 Production by Regulatory T Cells and Control of Experimental Autoimmune Encephalomyelitis

microRNAs (miRNA) are essential for regulatory T cell (Treg) function but little is known about the functional relevance of individual miRNA loci. We identified the miR-17–92 cluster as CD28 costimulation dependent, suggesting that it may be key for Treg development and function. Although overall im...

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Hlavní autoři: de Kouchkovsky, Dimitri, Esensten, Jonathan H., Rosenthal, Wendy L., Morar, Malika M., Bluestone, Jeffrey A., Jeker, Lukas T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160833/
https://ncbi.nlm.nih.gov/pubmed/23858035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203567
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