miR-17~92 promotes T follicular helper cell differentiation and represses subset-inappropriate gene expression

T follicular helper (T(FH)) cells are the prototypic helper T cell subset specialized to enable B cells to form germinal centers and produce high-affinity antibodies. We found that miRNA expression by T cells was essential for T(FH) cell differentiation. More specifically, we show that after protein...

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Autors principals: Baumjohann, Dirk, Kageyama, Robin, Clingan, Jonathan M., Morar, Malika M., Patel, Sana, de Kouchkovsky, Dimitri, Bannard, Oliver, Bluestone, Jeffrey A., Matloubian, Mehrdad, Ansel, K Mark, Jeker, Lukas T.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720769/
https://ncbi.nlm.nih.gov/pubmed/23812098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2642
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