Potent, Long-Acting Cyclopentane-1,3-Dione Thromboxane (A(2))-Receptor Antagonists

[Image: see text] A series of derivatives of the known thromboxane A(2) prostanoid (TP) receptor antagonists, 3-(6-((4-chlorophenyl)sulfonamido)-5,6,7,8-tetrahydronaphthalen-1-yl)propanoic acid and 3-(3-(2-((4-chlorophenyl)sulfonamido)ethyl)phenyl) propanoic acid, were synthesized in which the carbo...

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Autori principali: Wang, Xiaozhao, Liu, Li, Huang, Longchuan, Herbst-Robinson, Katie, Cornec, Anne-Sophie, James, Michael J., Sugiyama, Shimpei, Bassetto, Marcella, Brancale, Andrea, Trojanowski, John Q., Lee, Virginia M.-Y., Smith, Amos B., Brunden, Kurt R., Ballatore, Carlo
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2014
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160754/
https://ncbi.nlm.nih.gov/pubmed/25221659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml5002085
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