CCR5 as a Treatment Target in Pulmonary Arterial Hypertension

BACKGROUND: Pulmonary arterial hypertension (PH), whether idiopathic or related to underlying diseases such as HIV infection, results from complex vessel remodeling involving both pulmonary-artery smooth muscle cell (PA-SMC) proliferation and inflammation. CCR5, a co-receptor for cellular HIV-1 entr...

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Detalhes bibliográficos
Main Authors: Amsellem, Valérie, Lipskaia, Larissa, Abid, Shariq, Poupel, Lucie, Houssaini, Amal, Quarck, Rozenn, Marcos, Elisabeth, Mouraret, Nathalie, Parpaleix, Aurélien, Bobe, Régis, Gary-Bobo, Guillaume, Saker, Mirna, Dubois-Randé, Jean-Luc, Gladwin, Mark T, Norris, Karen A., Delcroix, Marion, Combadière, Christophe, Adnot, Serge
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160408/
https://ncbi.nlm.nih.gov/pubmed/24993099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.114.010757
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